Products
Radiopharmaceutical HOT CELLS
GMP shielded hot cells with integrated robots or telemanipulators for the formulation, dispensing, inspection, and packaging of radiopharmaceuticals.
Lead shielding protection (from 10mm to 180mm) and a frontal lead-glass provide maximum safety for operators.
Each phase of the production process is conducted with the latest generation equipment.
Certified ISO 7 and ISO 5 using validated processes that are constantly monitored and controlled.
Automatic vial and syringe dispensing solutions under a Grade A environment.
We provide turnkey HOT CELL & automation solutions for the production of radiopharmaceuticals
- Synthesis and Dispensing Hot Cells / Shielded Isolators (fully custom built) and Nuclear Isolators
- Vial Filling
- Capping and Crimping
- Particulate Matter, Cosmetic and Components Visual Inspection
- Radiation Inspection (Alpha and Beta)
- Labeling
- Cartoning
Complementary Technologies:
- Washing and Sterilization Lines
- Water treatment (WFI, PSG, storage tanks)
- Custom Automation
ACIC Machinery works closely with clients through all stages of a project from the planning and design phase to the integration, validation, and after-sales support.
Aseptic Vial Dispenser (N-FILL)
Compact stand-alone vial dispensing unit for nuclear medicine. The compact design of this unit allows it to fit in either a new or existing hot cell. For the end-user, this results in fewer rejections and in the best production performance. Each phase of the production process is conducted with the latest generation equipment; certified ISO 7 and ISO 5 using validated processes that are constantly monitored and controlled.
Automated vial disassembly, filling, stoppering, capping, and crimping.
- Customized dispensing unit
- IPC (100% In-Process Control) with retroactive feedback to the dosing system
- User-friendly and fast tool-free format change
- Compact footprint
- Output: 2-20 ppm
Semi-Automatic Vial Inspection
(N-ROBOX)
Semi-automatic inspection machine for glass vials containing radiopharmaceutical products.
Lead shielding protection (from 10mm to 180mm) and a front lead-glass provide maximum safety for operators.
The extremely compact design and the flexibility, given by the robot for handling the vials, makes ROBOX a unique and modular machine.
- Output: 3 to 15 vials/min
- Automatic picking of vials by robotic arm
- Particle inspection stations for visual inspection by an operator with white and black backgrounds
- Cosmetic inspection stations for visual inspection (vial body) by the operator with a vial rotation of 360°
- Cosmetic inspection station for visual inspection (bottom) by the operator with a vial rotation of 360°
- Dedicated illumination system
- User-friendly machine interface
- Operator buttons for automatic vial categorizing: Accepted, Reject, Re-inspection, and Dormant
- Automatic vials unloading by robotic arm
Production hot cell for formulation and dispensing (N-PRO)
Formulation, dispensing, inspection, labeling, and packaging hot cells for nuclear medicine.
Product formulation, filling, closing, and several controls are performed during 100% in-line production and are perfectly integrated into a lead-shielded system. For the end-user, this results in fewer rejects and the best production performances.
Each phase of the production process is conducted with the latest generation equipment.
Certified ISO 7 and ISO 5 using validated processes that are constantly monitored and controlled.
- Output: 2 to 40 vials/min
- Formulation hot cell
- Telemanipulator unit
- Activity safe cart
- Automatic dispensing hot cell
- Redundant filling system
- Customized vial dispensing unit
- Linear waste bunker
- 100% in-process control with retroactive feedback to the dosing system
- Automatic inspection hot cell
- Vial labeling hot cell
- Packaging hot cell
- Integrated dose calibrator
- Sample drawer and shielded cart
- Lead shielding from 10mm to 200mm (equivalent lead glass)
- Fast and easy tool-free format changeover process
